LIPASE

The lipase test is a blood test that measures lipase level in blood. This is an enzyme produced by pancreas. When present, lipases catalyse hydrolysis of fats into glycerol and fatty acids which are then absorbed by human body. This test is used to diagnose and monitor pancreatic disorders including pancreatitis, pancreatic cancer, cystic fibrosis among others. 

The lipase test involves taking small amount of your blood through venipuncture. Afterwards, it’s done at a lab where spectrophotometry technique is utilized to measure levels of lipase enzyme. 

In the blood, lipase levels are typically expressed as units per liter (U/L). Pancreatic dysfunction or disease may result from a high level of lipase while low levels can be a sign of pancreatic problem or other health complications. 

The lipase test is done when there is suspicion of a pancreatic disorder such as pancreatitis or when the patient has a known pancreatic problem, which needs to be monitored. It will also be ordered if: 

1. There is pain or tenderness in the abdomen 

2. Nausea and vomiting 

3. Fever 

4. Diarrhoea or oily stool 

5. A continuous loss of weight 

Taking a blood sample for lipase test does not involve any major risks as it is a routine procedure. However, just like other blood tests, some patients may experience pain or bruising at the site where needle was inserted. 

In rare cases, this examination can lead to: 

1. Dizziness and feeling faint 

2. Passing out 

3. Wound infection 

4. Allergy to antiseptic or latex used during testing 

Limitations of lipase test include: 

1. False negatives (if taken at early stages of disease) 

2. False positives (if the patient has an illness that affects its levels other than pancreas) 

3. And difficulty to interpret the results in patients with persistent pancreatitis or pancreatic cancer 

The lipase test measures how much of this enzyme is in the blood. Medical professionals search for: 

1. Amount of lipase: A raised level could mean a problem with your pancreas. 

2. Proportion of lipase to amylase: This ratio can diagnose pancreatitis. 

The doctor may recommend a lipase test if you have symptoms like abdominal pain, nausea, and vomiting which are associated with acute pancreatitis or if you have had pancreatitis previously. 

The lipase test helps identify and manage pancreatic problems at an early stage so that complications can be prevented before they occur. 

Lipase test could be suggested by a healthcare professional in case of these situations: 

1. Acute inflammation of the pancreas. 

2. Chronic inflammation of the pancreas. 

3. Pancreatic cancer. 

4. Cystic fibrosis. 

5. Pancreatic pseudocyst. 

The lipase test can help diagnose: 

1. Acute inflammation of the pancreas 

2. Chronic inflammation of the pancreas 

3 Pancreatic cancer 

4. Cystic fibrosis 

5. Pancreatic pseudocyst 

6. Pancreatic abscess 

To prepare for the lipase test: 

1. Fast for 8–12 hours before a lipase test, avoiding food, drinks (except water), and certain medications if instructed. 

2. Stay hydrated, wear comfortable clothing, and follow your doctor’s specific instructions for accurate results. 

Prerequisites: Fasting for 8-12 hours before the test is required 

Eligibility: Any age group is eligible to undergo lipase testing. 

Procedure for Taking the Test: A healthcare provider uses a needle and syringe to draw blood from a vein in your arm. Afterward, this sample will be taken to a lab where it will be analysed. 

Caution Before the Test: Let your doctor know about any drugs, vitamins and herbs you are using since they may affect your test results.