MRI BREAST WITH CONTRAST

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About The Test

Breast MRI Scan with Contrast: Overview, Uses & Importance

MRI of the breast with contrast is a sensitive imaging method that enhances the evaluation of breast tissues, cancer detection, and surveillance in high-risk patients. The use of contrast material (usually gadolinium) improves clarity and allows for clearer visualization of abnormal tissues, tumours, and blood vessels.  

What is a Breast MRI Test with Contrast and How Does It Work? 

MRI of the breast with contrast is an advanced diagnostic technique that utilizes magnetic fields and gadolinium-based dyes to illuminate pathological tissue, providing thorough three-dimensional views of both breasts, capturing and discerning even minute tumours which might remain hidden in mammograms or ultrasounds. 

List of Parameters

Key Parameters in Breast MRI Test with Contrast Interpretation

  • Time elapsed since breast injections to be evaluated post contrast 15minutes 
  • Age of girl 
  • Mass, contours and borders of the lesions 
  • Involvement of the axillary lymph node 
  • Degree of breast regarded as normal post-surgery and post treatment 

Why This Test

Top Reasons for Recommending a Breast MRI Scan with Contrast

  • Evaluation checks post MRI, chemotherapy undertaken, or surgery with the goal of intervention such as repeat surgery. 
  • Establish targets for lesions goals post the initial intervention. 
  • Identify possibilities for advanced treatments due to incomplete response or new lesions. 
  • Evaluating breast implants for leaks and ruptured implants 

When and Who Should Get a Breast MRI Scan with Contrast? 

Clearing and Criteria 

  • Undergoing routine screening for pits of high-risk breast cancer 
  • Breast cancer patients under therapy as per treatment responses and staging 
  • Breast implant assessment 
  • Abnormal thickening or nipple discharge without obvious explanation. 
  • Unexplained ultrasound or mammogram results 

Relevant Patients: 

  • Women with known familial or genetic predisposition such as BRCA1/2 positive. 
  • Diagnosed breast cancer patients. 
  • Patients with dense breasts. 
  • Patients on active monitoring for chemotherapy or hormone therapy. 

Benefits

Benefits of Breast MRI Test with Contrast for Cancer Detection

  • Outstanding for identifying cancer 
  • Excellent for women with dense breasts 
  • A multifaceted assessment that combines functional and physical evaluation 
  • Capable of detecting multifocal or bilateral disease 
  • Requires no invasive techniques and is safe when certain guidelines are followed 

Conditions Diagnosed Using Breast MRI Scan with Contrast

  • Invasive breast cancer 
  • Ductal carcinoma in situ (DCIS) 
  • Multifocal/multicentric disease 
  • Axillary lymphadenopathy 
  • Post-surgical scar or recurrence 
  • Ruptured or leaking implants 
  • Benign tumours such as fibroadenomas and cysts 

Preparing for test

How to Prepare for a Breast MRI Test with Contrast

  • Schedule an appointment in the 7–14-day window post menstruation (for premenopausal women)  
  • Do not apply any creams, deodorants, or powders the day of the examination 
  • Remove all metal items including jewellery 
  • Drink enough water before and after the appointment, especially for those requiring contrast imaging 
  • Advise the technician of any previous surgeries, implants, allergic reactions, and other pertinent medical history 

Pre-requisites Before Getting a Breast MRI Scan with Contrast 

  • Doctor’s referral letter stipulating pathology warranting an MRI 
  • Assessment of renal function (eGFR) if contrast MRI is planned 
  • Ultrasound or mammogram may be a prerequisite before MRI 
  • Documented clinical background with details of the menstrual cycle 

Best Time to Perform a Breast MRI Scan with Contrast 

  • Day 7-14 of menstrual cycle for premenopausal patients 
  • Prior to surgical intervention or biopsy 
  • Post chemotherapy for evaluating the response to treatment 

Eligibility for Breast MRI Test with Contrast 

  • Women with confirmed or potential breast malignancy 
  • Patients with a significant family history or pathological predisposition 
  • Implant holders with a presumed rupture 
  • Not appropriate for persons with MRI non-compatible >implants or severe renal insufficiency 

Breast MRI with Contrast Procedure 

  • The patient is positioned prone with the breasts cantered into dedicated breast coils. 
  • An intravenous (IV) access is established for contrast (gadolinium) injection. 
  • Image acquisitions are done prior and after contrast injection. 
  • Scan time ranges from 30 to 45 minutes. 
  • Constant minimal movement is required from the patient throughout the duration of the procedure. 

Caution During a Breast MRI Scan with Contrast 

  • Assess renal function prior to gadolinium administration. 
  • Screen for metal implants, reactions to contrast, and other allergies. 
  • Notify if they are pregnant, lactating, or taking any therapies. 

Test Results

Results and Interpretations

Condition/Findings Description Interpretation
Malignant tumour Abnormal enhancement with irregular borders. Suggestive of breast cancer.
Benign lesion Smooth borders and slow enhancement. Often fibroadenomas or cysts.
Implant rupture Irregular shape, silicone leak signs. Indicates intracapsular or extracapsular rupture.
Post-treatment changes Scar tissue or fat necrosis. Differentiated from recurrence by enhancement pattern.
DCIS Non-mass-like enhancement. May show segmental linear enhancement.

FAQs

Is MRI Breast with Contrast Safe?

In most cases, this is safe. Gadolinium is the contrast agent utilized and is well tolerated by most patients with normal functioning kidneys.  

Can it detect all types of breast cancer?

It misses some microcalcifications but is incredibly accurate for invasive cancers.  

Do I need contrast for every breast MRI?

Yes, contrast is very important for an accurate diagnosis and more than one ancillary study.  

Can it be done with implants?

Yes, and it is the best modality for detecting implant rupture. 

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